← Blood Choices Blood Fraction
Clotting Factors
What it is
Specific proteins extracted from plasma that help blood clot. Essential for treating hemophilia and other bleeding disorders.
Derived from: Plasma
If you accept vs. refuse
Accept Why some people accept
- Essential for treating hemophilia and bleeding disorders
- Recombinant (synthetic) versions are available that aren't derived from donated blood
- Many who refuse primary components consider fractions a personal decision
Refuse Why some people refuse
- Plasma-derived versions come from donated blood
- Some consider any blood derivative to be equivalent to whole blood
- Recombinant versions may be an acceptable alternative
Alternatives
Pharmaceutical Desmopressin (DDAVP) A synthetic hormone that promotes clotting by releasing von Willebrand factor. Used to reduce bleeding in certain surgical settings.
Related concepts
Topic Fractions: The Personal Decision Blood fractions are smaller derivatives of primary components. Whether to accept them is considered a personal conscience decision by many.
Blood Fraction Immunoglobulins Antibody proteins extracted from donated plasma. Used to boost immune response or treat autoimmune conditions. Medical references
In your Directive
Your directive will record your decision on clotting factor concentrates. If you refuse plasma-derived but accept recombinant versions, note this in special instructions.
Make this choice in your Directive
Your blood product decisions are recorded clearly and shared with your Care Team.
Create your Directive